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FOR IMMEDIATE RELEASE
Nutritional and Antioxidant Therapy Reverses Opioid Dependence and Liver Cirrhosis: A Case ReportBy Aarti Midha, M.D., and Pankaj Verma, M.D. ✒️ Editor's NoteThis case report has been edited for clarity, readability, and accessibility for Orthomolecular Medicine News Service (OMNS) readers. The original, full-length clinical version can be downloaded separately. [Download Full Clinical Version] 🔹 Key Highlights✅ Opioid withdrawal completed in 30 days using integrative nutritional protocols-without relapse. ✅ Liver fibrosis reversed over six months, documented by FibroScan. ✅ Addressed gut-liver-brain axis dysfunction with probiotics, antifungals, and dietary changes. ✅ Corrected deficiencies in taurine, tyrosine, vitamin D3, and magnesium. ✅ Reduced oxidative stress with NAC, alpha-lipoic acid, vitamin C, and glutathione. ✅ Used low-dose medications (metformin, pregabalin, clonidine) to support the transition. ✅ Demonstrates a safe, effective orthomolecular alternative to drug-centered treatment. 🔬 BackgroundConventional medicine often isolates liver disease from psychiatric conditions like opioid dependence. But both disorders share root causes and common mechanisms-namely micronutrient deficiency, oxidative stress, gut dysbiosis, and neurotransmitter imbalances. This case report illustrates the reversal of both conditions using a structured integrative plan based on orthomolecular principles. 🧠 Case OverviewA young man from Punjab presented in 2022 with:
🛠️ Treatment Strategy
📈 Outcomes
🧩 DiscussionGut-Liver-Brain AxisGut dysbiosis fuels systemic inflammation in both cirrhosis and addiction. Probiotics, antifungals, and a clean diet improved microbiome balance and reduced endotoxemia. Antioxidant DefenseChronic opioid use and liver disease both generate intense oxidative stress. NAC, ALA, vitamin C, and glutathione collectively reduced free radical damage and improved hepatic function. Amino Acid and Neurotransmitter SupportTaurine and tyrosine replenishment helped normalize mood and energy. These amino acids are essential for neural stability and liver regeneration. Metabolic RegulationMetformin improved insulin resistance. Clonidine and pregabalin reduced sympathetic overdrive, easing withdrawal and supporting neurotransmitter balance. 🧠 ConclusionThis case shows how integrative orthomolecular medicine-by addressing micronutrient depletion, gut dysbiosis, oxidative stress, and neurochemical imbalances-can reverse complex, comorbid conditions previously considered intractable. It highlights a non-pharmacological pathway to healing, and a model for future clinical strategies. 👩⚕️ About the AuthorsAarti Midha, M.D. is a psychiatrist and board-certified anti-aging medicine specialist from Jaipur, India. She specializes in metabolic and nutritional psychiatry. Pankaj Verma, M.D. is an internal medicine consultant focused on integrative liver, diabetes, and metabolic care. Orthomolecular MedicineOrthomolecular medicine uses safe, effective nutritional therapy to fight illness. For more information: http://www.orthomolecular.org Find a DoctorTo locate an orthomolecular physician near you: http://orthomolecular.org/resources/omns/v06n09.shtml The peer-reviewed Orthomolecular Medicine News Service is a non-profit and non-commercial informational resource. Editorial Review Board:
Jennifer L. Aliano, M.S., L.Ac., C.C.N. (USA)
Comments and media contact: editor@orthomolecular.org OMNS welcomes but is unable to respond to individual reader emails. Reader comments become the property of OMNS and may or may not be used for publication. Click here to see a web copy of this news release: https://orthomolecular.acemlna.com/p_v.php?l=1&c=452&m=397&s=bad97c655476f96a390a72c05a742011 |
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